DHT is an androgen that is made by converting testosterone into DHT via 5ar reductase.
It is responsible for multiple androgenic physical effects during puberty, and 5ar reductase is also associated with several bodily functions, such as regulating the circadian rhythm of the body.
There are 3 isoforms of DHT which are located in different tissues of the body,
Type 1: present in most tissues
Type 2: present in genital tissues (non skin) and hair. Found in the prostate, and liver.
Type 3: Wide tissue distribution, including the brain, skin, ovary, small intestine, and kidney.
DHT is responsible for physical effects such as acne, bottom growth, and hair loss. When these effects are an undesirable element of transition (or leftover effects from first puberty) you may want to use pharmaceutical or natural methods to lower your DHT.
If you want more information about reducing erections or bottom growth, visit the article on NOS and bottom growth, then go to the section on “NOS inhibitors”. I believe that NO reduction combined with DHT reduction could be a potent inhibitor of bottom growth.
Pharmaceutical 5ar inhibitors on the market include finasteride and dutasteride.
Natural 5ar/DHT inhibitors include:
- EGCG downregulates DHT and T by reducing the transcription of androgen receptors. EGCG is found in black and green tea, and the most in green tea. Matcha tea has a much higher EGCG content. https://www.ncbi.nlm.nih.gov/pubmed/14518774 Green tea leads to blood vessel relaxation, however. www.jbc.org/content/279/7/6190.full Green tea is also a nonsteriodal inhibitor of 5ar reductase.
- You may also want to look into topical botanicals that possibly inhibit DHT, such as pumpkin seed oil and saw palmetto. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017725
- A compound found in vegetables (Indole-3-carbinol) inhibits and downregulates AR, at least in cancerous prostate cells. (https://www.ncbi.nlm.nih.gov/pubmed/15958518)
- Aromatase production (more E) combined with a 5ar inhbibitor downregulates AR in the corpora cavernosum, which is where erections occur.
- Flax seed https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752973/
- Fenugreek https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752973/
- Curcumin https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693613/
- GLA https://www.ncbi.nlm.nih.gov/pubmed/11380153
- Saw palmetto https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002402/
- Black pepper https://www.thieme-connect.com/products/ejournals/html/10.1055/s-0035-1546082
- Pumpkin seed oil https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017725/
- Nettle root
- Red reishi https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693613/
- Nettle root https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405682/
- Cinnamon https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994048/